PREDICTED: Homo sapiens hypothetical LOC342979 (LOC342979), mRNA. zinc ion binding [goid 8270] [evidence IEA]; metal ion binding [goid 46872] [evidence IEA], CTAGCAGGGAGCGGTGAGGGAGAGCGGCTGGATTTCTTGCGGGATCTGCA. Lipoprotein apheresis is also approved during pregnancy and considered safe for very high risk women with known significant atherosclerotic disease or HoFH.1 Healthy lifestyle with low-fat, low-cholesterol diet and routine exercise are strongly recommend before, during and after pregnancy. PROSPECT SUMMARY. Women with FH need counseling on risk reduction and management with particular attention on therapy during pre-conception, pregnancy, childbirth and lactation. Genome-wide analysis of androgen receptor (AR) SUMOylation effects on gene expression (HEK293). Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. The decision to have children and duration of breastfeeding are personal choices for each woman and these choices need to be individually examined by her health care providers. membrane [goid 16020] [evidence IEA]; integral to membrane [goid 16021] [evidence IEA]; endoplasmic reticulum [goid 5783] [evidence IEA], lipid biosynthesis [goid 8610] [evidence IEA]; lipid metabolism [goid 6629] [evidence IEA], acyltransferase activity [goid 8415] [evidence IEA]; transferase activity [goid 16740] [evidence IEA], GTCCCCAACCCTAACCCGGACCTGGCACATACAAGACATTCAGCAGATGG. SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner. Homo sapiens chromosome 15 open reading frame 39 (C15orf39), mRNA. Genetic, functional and molecular features of glucocorticoid receptor binding, Genome-wide analysis of gene expression in bladder cancer cell lines 253JB-V and UM-UC13 exposed to bortezomib, Genome-wide analysis of each stage of EPCs differentiation, Gene expression profile of ETV1 knockdown in LNCaP prostate cancer cells, A broad array of anticancer activities of the immunosuppressive drug mycophenolic acid (MPA) is suggested by pathway analyses of gene expression and validated by proteomic and functional assays, Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders, Gene expression analysis of omental and mesenteric adipose tissue in Crohn's disease and ulcerative colitis, Transcriptome-based network analysis reveals a spectrum model of human macrophage activation [Expression], Transcriptome-based network analysis reveals a spectrum model of human macrophage activation, ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss, Expression and functional pathway analysis of nuclear receptor NR2F2 in Ovarian cancer, Regulation of Gene Expression by Connective Tissue Growth Factor (CTGF) in Mesenchymal Stromal Cells (MSCs), Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage [expression], Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage, Global peripheral blood gene expression study [HumanHT-12 V3.0], Global peripheral blood gene expression study, Co-regulated gene expression by estrogen receptor-α and liver receptor homolog-1 is a feature of the estrogen response in breast cancer cells, Time series of global gene expression after trivalent influenza vaccination in humans (male cohort), Time series of global gene expression after trivalent influenza vaccination in humans, Identification of subsets of urothelial carcinoma, Crosstalk between the STAT3, NF-kB and Notch signaling pathways in glioblastoma stem cells, SRT2014 and the whole blood leukocyte transcriptional response during human endotoxemia. A Daphnane Diterpenoid Isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity, Synthetic lethal screening with small molecule inhibitors provides a pathway to rational combination therapies for melanoma, Nanotoxicogenomic study of ZnO and TiO2 responses (Illumina), Feed-forward Inhibition of Androgen Receptor Activity by Glucocorticoid Action in Human Adipocytes, Nanotoxicogenomic study of ZnO and TiO2 responses, GATA3 acts upstream of FOXA1 in mediating ER binding by shaping enhancer accessibility, FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells (mRNA), FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells, Transient transfection of C28/I2 chondrocytes; the human EST DA125942 (CISTR-ACT's lncRNA) was overexpressed and siRNA-depleted, Transcriptional profiling of gastric epithelial cells infected with wild type or arginase-deficient Helicobacter pylori, Aberrant choline metabolism in epithelial ovarian cancer: relevance of choline kinase activity and expression, Blood transcriptome of human bacterial and influenza A pneumonia, Transcriptomic analysis of a gut epithelial cell line after the depletion of selenoprotein Glutathione peroxidase 4, MicroRNA-520c-3p targets eIF4GII and acts as a tumor suppressor in diffuse large B cell lymphoma, Transcriptional analysis of whole blood in patients with auto-inflammatory disorders, The effect of TRPM2-AS depletion in human prostate carcinoma PC3 cell line, A gene expression signature of PDGF-stimulated fibroblasts, Transcriptional analysis of whole blood, primary fibroblasts, and PBMCs upon TNF-alpha or IL-1beta stimulation from HOIL-1-deficient patients, Conversion of human fibroblasts into vascular cells (gene expression), Conversion of human fibroblasts into vascular cells, Baseline expressions in human whole blood, Disease-specific sequence change DSC3 in TAF1/DYT3 affects genes in vesicular transport and dopamine metabolism. PCSK9 inhibitors have not been tested for safety during pregnancy and are not currently approved during pregnancy. Read More It is not known whether lomitapide or mipomersen are excreted in breast milk. Formalin Fixation at Low Temperature Better Preserves Nucleic Acid Integrity, HDACI and DAC induce specific epigenetic profile in DLBCL, Hedgehog/GLI signalling and hormone independence in prostate cancer (PCa) cell lines, Gene expression profiles elicited by estradiol and endoxifen in MCF7 parental and ER-beta expressing breast cancer cells. The mRNA levels of CD133 positive and CD133 negative cells after radiation exposure, Gene expression profiling of breast carcinomas using leftovers from diagnostic Fine Needle Aspiration Cytology. However, women with FH and previous myocardial infarction, myocardial ischemia or left ventricular dysfunction should have counseling on risk of CVD during pregnancy. CTGGAAAAGCAAAATTTGGATTTGTGGTTCAATCCACCATCTTTACTCAG, EST53225 Fetal heart II Homo sapiens cDNA 3 end, mRNA sequence, ATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAACATGGAGGC. Whole-transcriptome gene expression profiling in TRPC1-silenced cells. Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer. When a woman with FH is ready to conceive, statins, ezetimibe and niacin should be stopped at least 4 weeks prior to discontinuing contraception according to the NLA recommendations for FH,1 whereas others recommend discontinuing statins approximately three months prior to attempting conception.4,6 Women who become pregnant while on statin therapy should stop the statin immediately and undergo fetal assessment with a maternal-fetal specialist as soon as possible.1 These women who accidentally become pregnant on statin therapy may also be reassured that the likelihood is low for fetal complications.4 More recent observational studies reviewing multiple clinical studies and case reports did not report an increased risk of congenital anomalies with statin exposure in pregnancy when compared to control groups or the prevalence of congenital anomalies in the general population.7, Women with FH may have more conditions associated with pregnancy-related complications such as diabetes, hypertension disorders, renal dysfunction and polycystic ovarian syndrome, which is also associated with infertility. Genome-wide analysis gene expression in SUM-149 cells expressing AREG shRNA, The effects of EBV transformation on gene expression, The effects of EBV transformation on gene expression and methylation levels, Genome-wide analysis gene expression of MCF10A cells growing in the presence of EGF or AREG or without EGF or AREG for 24 hrs, MOLECULAR CHARACTERIZATION OF LIVER ALLOGRAFTS FROM OPERATIONALLY TOLERANT TRANSPLANT RECIPIENTS (Illumina), MOLECULAR CHARACTERIZATION OF LIVER ALLOGRAFTS FROM OPERATIONALLY TOLERANT TRANSPLANT RECIPIENTS, Identification of STAT5 target genes in human CB HSC, CMP, GMP and MEP, Gene expression analysis of FSHD muscle with different MRI pattern, Nociceptor differentiation from pluripotent cells, Characterization of gene expression profiles of gastric cancer in the Korea University cohort, Characterization of gene expression profiles of gastric cancer in Kosin University cohort, Characterization of gene expression profiles of gastric cancer, Discovery of Shear- and Side-specific mRNAs and miRNAs in Human Aortic Valvular Endothelial Cells, Analysis of Promoter Methylation in Breast Cancer. Response of peripheral blood mononuclear cells to peptide stimuli, Diagnosis of childhood bacterial and viral infection using host RNA expression [validation set], Diagnosis of childhood bacterial and viral infection using host RNA expression. A recent study of mostly Italian patients showed significant premature atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. GTGCCAGCTGCCATTGCACTGCCTCACATTTTCCTTTAGATGTTTGAGCA, BX093329 Soares_parathyroid_tumor_NbHPA Homo sapiens cDNA clone IMAGp998A124183 ; IMAGE:1648403, mRNA sequence, CTTGCCTAGAGAACACACATGGGCTTTGGAGCCCGACAGACCTGGGCTTG. Serial single-gene testing involves sequence analysis of LDLR first followed by LDLR deletion/duplication analysis if no pathogenic variant is found. Genome-wide espression kinetics of children progressing to clinical Type 1 diabetes (T1D). Transcript and protein profiling identify signaling, growth arrest, apoptosis and NFκB-survival signatures following GnRH receptor activation. PREDICTED: Homo sapiens similar to small EDRK-rich factor 1A, telomeric, transcript variant 4 (LOC728492), mRNA. Overcoming chemoresistance in B lymphoma cells: elucidating the role of NF-kB in caspase-independent apoptosis by transcriptomic assessment. Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association. Two different 4-week energy-restricted diets. The Postal Accountability and Enhancement Act (PAEA) is a United States federal statute enacted by the 109th United States Congress and signed into law by President George W. Bush on December 20, 2006.. Expression data profile of A498 cells inoculated with E. coli 83972 and E. coli CFT073, Gene profile from RND1-knock down in MDF10A cells, Expression data of host gene response to Escherichia coli 83972, Genetic, functional and molecular features of glucocorticoid receptor binding (expression), IFNa and IL4 DCs stimulated with microbial components for 6hr, Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines, Genome-wide analysis of muscle gene expression in response to an intense cycling exercise. Choose from a variety of plastic and polymer bearings, washers, and bushings as well as linear slides and guides, flexible cable, drag chains, cable tracks, cable carriers, and energy chains. Non-statins such as ezetimibe, niacin and fibrates have also been associated with teratogenicity and are therefore not indicated during pregnancy. Gene Expression Profiling of Primary Male Breast Cancers Reveals Two Unique Subgroups and Identifies N-acetyltransferase-1 (NAT1) as a Novel Prognostic Biomarker, Gene expression profiling of normal lung tissue adjacent to lung adenocarcinoma (ADCA), Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast, Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer, A Comparative Analysis of the Transcriptome of Hypoxia and Inflammation in Swan 71 Human Trophophoblast Cells: Its Implications in Preeclampsia, Relationship between Genome-Wide DNA Methylation and Gene Expression in Uterine Leiomyoma, Metronomic doxorubicin blocks HIF-1α-mediated responses in sarcomas and augments the effects of anti-VEGF-A therapy, Investigation of Isogenic Human Embryonic Stem Cells and Derived Induced Pluripotent Stem Cells and Differentiated Line, Prognostic DNA Methylation Patterns in Cytogenetically Normal Acute Myeloid Leukemia are predefined by Stem Cell Chromatin Marks [gene expression], Genome-wide gene expression analysis of neurofibroma-derived NF1+/- and NF1-/- Schwann cells, Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers [expression data], The response of human primary airway epithelial cells to Influenza or RSV infection [hAECs_Illumina], The response of PBMCs and primary airway epithelial cells to Influenza and RSV virus, Prognostic DNA Methylation Patterns in CN-AML; a genome wide methylation and gene expression study, Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers, Genome-wide analysis of gene expression profiles in colorectal cancer cells treated with boswellic acids, Boswellic acid induced changes in gene expression and methylation in colorectal cancer cells, Regulation of gene expression by GLIPR1 in prostate cancer cells, Hyperglycemia and a Common Variant of GCKR Are Associated with the Levels of Eight Amino Acids in 9,371 Finnish Men, Integrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (gene expression), Integrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma, Gene signatures in prostate cancer linked to the Gleason score. miR-126 over-expression in highly metastatic LM2 breast cancer cells. Gene expression analyses of miR-99b and miR-330-3p overexpression in Natural killer cells, RNAi-mediated MLL/AF4 knock-down time course, Hormetic shifting of redox environment by the ROS-producing polyphenol resveratrol protects cells from oxidative stress. All Publications/Website. Using Blood-Informative Transcripts in Geographical Genomics: Impact of Lifestyle on Gene Expression in Fijians. ubiquitin cycle [goid 6512] [evidence IEA], zinc ion binding [goid 8270] [evidence IEA]; metal ion binding [goid 46872] [evidence IEA]; metallopeptidase activity [goid 8237] [evidence IEA]; ubiquitin thiolesterase activity [goid 4221] [evidence IEA], bA399O19.2; AMSH-LP; ALMalpha; KIAA1373; FLJ31524; AMSH-FP, ACCGCAGAGCCTTTGACCTCGGTACCTCAATATGAAGATTCAGGGTCTTC, xo15e10.x1 NCI_CGAP_Ut2 Homo sapiens cDNA clone IMAGE:2704074 3, mRNA sequence, TAATCAGGACCCAGCAAATTTCCCCGAAGCAATGGGGTCCCGGTGGGCTC, AGENCOURT_10400114 NIH_MGC_82 Homo sapiens cDNA clone IMAGE:6616301 5, mRNA sequence, GAAAGAGATTTTGGTAGGAGAGGGCTGAGGCTGACAGCGGGGAGATGCCA, he12d07.x1 NCI_CGAP_CML1 Homo sapiens cDNA clone IMAGE:2918797 3, mRNA sequence, CAGCCTCTGTGTGAGTGGATGATTCAGGTTGCCAGAGACAGAACCCTCAG, CCACCGAGGGTGAAGAGGCAAGTGGCCCTAAGCAAAAGACGTGCCAGTGT. Molecular diversity of breast cancers at the time of endocrine resistance [mRNA], Molecular diversity of breast cancers at the time of endocrine resistance, Whole blood transcriptome of survivors and nonsurvivors of sepsis, Expression data from human brain anterior cingulate cortex - including control samples and samples with major depression disorders (20 samples MD2_ACC), Expression data from human brain anterior cingulate cortex - including control samples and samples with major depression disorders (50 samples MD3_ACC), Expression data from human brain amygdala - including control samples and samples with major depression disorders (42 samples MD3_AMY), A molecular profile of chronic cocaine abuse includes differential expression of genes regulating transcription, chromatin and dopamine cell phenotype, Gene expression patterns of a novel breast cancer cell line derived from a bone metastatic lesion of a breast cancer patient, Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias [expression], Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias, Gene expression analysis of FOXN1+ thymic endoderm cells derived from the in vitro differentiation of human embryonic stem cells, Extracellular Superoxide Dismutase Regulates the Expression of GTPase Guanine Nucleotide Exchange Factors (GEFs), GTPase-activating proteins (GAPs), and Rho Guanine nucleotide disassociation inhibitors (GDI), Gene expression profiles from joint-matched macroscopically intact and OA affected cartilage of patients undergoing joint replacement surgery due to end-stage OA, Association between alpha-synuclein blood transcripts and early Parkinson's disease, Transcriptional landscape of aging in humans, Endometriosis: Normal endometrial stromal cells and endometriotic stromal cells, Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanomas, Suppression of NCALD protects against spinal muscular atrophy by restoring impaired endocytosis, Long non-coding Satellite III RNAs link the heat shock response and cell proliferation, Molecular profiling of ovarian carcinoma platinum-sensitive and -resistant cell lines (gene expression), Molecular profiling of ovarian carcinoma platinum-sensitive and -resistant cell lines, The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines, Genome-wide transcription profiling of 22q11.2 deletion syndrome reveals functional pathways related to phenotypic expression of psychosis and autism spectrum disorder, Genome wide transcriptomic analysis of sarcomatoid (E/S), rhabdoid (E/R) and non-sarcomatoid (E*) clear cell renal cell carcinoma, Genome wide analysis of sarcomatoid and non-sarcomatoid clear cell renal cell carcinoma, Genetic Neuropathology of Obsessive Psychiatric Syndromes, Transcription profiling by array of epidermal shave samples taken from lesional and non-lesional skin from German atopic dermatitis patients and from healthy skin from German controls, Reduced gene expression levels after chronic exposure to high concentrations of air pollutants, Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells, Genome wide expression profiling of mesenchymal stem cells of fetal and adult origin and dermal fibroblasts, Chronic clinical hepatic schistosomiasis japonica, Modified Stat1 Confers Enhanced Interferon Responsiveness and Improved Baseline Antiviral Host Defense, PARP9 and DTX3L in Antiviral Host Defense. FH is one of the most common genetic disorder found in children.13 All children of FH mothers should undergo lipid screening by age 2. A recent commentary on statins and breastfeeding in FH suggests that the practice of withholding statin therapy during breastfeeding in women with FH should be reconsidered as there are natural benefits to breastfeeding for the mother and the newborn.12 Also, there may be limited risk of the statins in the breast milk as statins are cleared in the liver and have minimal pharmacologic effect on the child.
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